Viral channel proteins in intracellular protein-protein communication: Vpu of HIV-1, E5 of HPV16 and p7 of HCV

Wolfgang B. Fischer*, Li Hua Li, Dhani Ram Mahato, Yi Ting Wang, Chin Pei Chen

*此作品的通信作者

研究成果: Review article同行評審

10 引文 斯高帕斯(Scopus)

摘要

Viral channel forming proteins are known for their capability to make the lipid membrane of the host cell and its subcellular compartments permeable to ions and small compounds. There is increasing evidence that some of the representatives of this class of proteins are also strongly interacting with host proteins and the effectiveness of this interaction seems to be high. Interaction of viral channel proteins with host factors has been proposed by bioinformatics approaches and has also been identified experimentally. An overview of the interactions with host proteins is given for Vpu from HIV-1, E5 from HPV-16 and p7 from HCV. This article is part of a Special Issue entitled: Viral Membrane Proteins - Channels for Cellular Networking.

原文English
頁(從 - 到)1113-1121
頁數9
期刊Biochimica et Biophysica Acta - Biomembranes
1838
發行號4
DOIs
出版狀態Published - 4月 2014

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