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Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy
Yi Ju Chou
, Ching Cheng Lin
,
Ivan Dzhagalov
,
Nien Jung Chen
,
Chao Hsiung Lin
, Chun Cheng Lin
,
Szu Ting Chen
, Kuo Hsin Chen
,
Shu Ling Fu
*
*
此作品的通信作者
微生物及免疫學研究所
生命科學系暨基因體科學研究所
臨床醫學研究所
傳統醫藥研究所
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引文 斯高帕斯(Scopus)
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Keyphrases
Autophagy
100%
Vaccine Adjuvant
100%
Adjuvant Activity
100%
Synthetic Glycolipid
100%
TLR4
100%
RAW264.7 Cells
40%
Toll-like
40%
Antigen Processing
40%
Bone Marrow-derived Macrophages
40%
Macrophages
20%
Interleukin-2
20%
Immunization
20%
Receptor-mediated
20%
Monocytes
20%
Activated T Cells
20%
NF-B
20%
Adaptive Immunity
20%
Immune Response
20%
Antigen-presenting Cells
20%
Antigen-specific Immune Response
20%
Antigen Presentation
20%
Innate Immunity
20%
RB Pathway
20%
Autophagy Inhibitor
20%
Antigen-specific
20%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
20%
3-methyladenine (3-MA)
20%
Peritoneal Cavity
20%
Beclin-1
20%
Antigen-specific Response
20%
Serum Biochemical Profile
20%
Antigen-specific CD4 T Cells
20%
Immune Adjuvant
20%
Processing Activities
20%
Host Immune Defense
20%
Autophagy-related
20%
Specific IgE
20%
Immunology and Microbiology
TLR4
100%
Autophagy
100%
Vaccine Adjuvant
100%
Glycolipid
100%
Antigen Specificity
57%
Antigen Presentation
42%
Adjuvant
28%
Immune Response
28%
Bone Marrow-Derived Macrophage
28%
Toll-Like Receptor
28%
Macrophage
14%
T Cell
14%
Innate Immune System
14%
Monocyte
14%
Cytokine
14%
Adaptive Immune System
14%
Interleukin 2
14%
T-Helper Cell
14%
Transcription Factor Nrf2
14%
Peritoneal Cavity
14%
Antigen Presenting Cell
14%