Ultrasound ionization of biomolecules

Chen I. Wu; Yi Sheng Wang; G. Chen; Chung Yi Wu; Chung Hsuan Chen

doi:10.1002/rcm.4677

Ultrasound ionization of biomolecules

Chen I. Wu, Yi Sheng Wang, G. Chen, Chung Yi Wu, Chung Hsuan Chen^*

^*此作品的通信作者

電機工程學系

研究成果: Article › 同行評審

17 引文斯高帕斯（Scopus）

摘要

To date, mass spectrometric analysis of biomolecules has been primarily performed with either matrix-assisted laser desorption/ionization (MALDI) or electrospray ionization (ESI). In this work, ultrasound produced by a simple piezoelectric device is shown as an alternative method for soft ionization of biomolecules. Precursor ions of proteins, saccharides and fatty acids showed little fragmentation. Cavitation is considered as a primary mechanism for the ionization of biomolecules.

原文	English
頁（從 - 到）	2569-2574
頁數	6
期刊	Rapid Communications in Mass Spectrometry
卷	24
發行號	17
DOIs	https://doi.org/10.1002/rcm.4677
出版狀態	Published - 15 9月 2010

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10.1002/rcm.4677

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AU - Wu, Chen I.

AU - Wang, Yi Sheng

AU - Chen, G.

AU - Wu, Chung Yi

AU - Chen, Chung Hsuan

PY - 2010/9/15

Y1 - 2010/9/15

N2 - To date, mass spectrometric analysis of biomolecules has been primarily performed with either matrix-assisted laser desorption/ionization (MALDI) or electrospray ionization (ESI). In this work, ultrasound produced by a simple piezoelectric device is shown as an alternative method for soft ionization of biomolecules. Precursor ions of proteins, saccharides and fatty acids showed little fragmentation. Cavitation is considered as a primary mechanism for the ionization of biomolecules.

AB - To date, mass spectrometric analysis of biomolecules has been primarily performed with either matrix-assisted laser desorption/ionization (MALDI) or electrospray ionization (ESI). In this work, ultrasound produced by a simple piezoelectric device is shown as an alternative method for soft ionization of biomolecules. Precursor ions of proteins, saccharides and fatty acids showed little fragmentation. Cavitation is considered as a primary mechanism for the ionization of biomolecules.

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JO - Rapid Communications in Mass Spectrometry

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Ultrasound ionization of biomolecules

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