Treatment for the endocrine resistant breast cancer: Current options and future perspectives

Chun Yu Liu; Chia Yun Wu; Karineh Petrossian; Tzu Ting Huang; Ling Ming Tseng; Shiuan Chen

doi:10.1016/j.jsbmb.2017.07.001

Treatment for the endocrine resistant breast cancer: Current options and future perspectives

Chun Yu Liu, Chia Yun Wu, Karineh Petrossian, Tzu Ting Huang, Ling Ming Tseng, Shiuan Chen^*

^*此作品的通信作者

醫學系內科學科

研究成果: Review article › 同行評審

42 引文斯高帕斯（Scopus）

摘要

Endocrine resistance remains a challenge and an unmet need for managing hormone receptor-positive breast cancer. The mechanisms of endocrine resistance are multifaceted and are likely to evolve over time following various single or combination therapies. The purpose of this review article is to provide general understanding of molecular basis of endocrine resistance of breast cancer and to offer comprehensive review on current treatment options and potential new treatment strategies for endocrine resistant breast cancers. Last but not the least, we discuss current challenges and future directions for management of endocrine resistant breast cancers.

原文	English
頁（從 - 到）	166-175
頁數	10
期刊	Journal of Steroid Biochemistry and Molecular Biology
卷	172
DOIs	https://doi.org/10.1016/j.jsbmb.2017.07.001
出版狀態	Published - 9月 2017

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title = "Treatment for the endocrine resistant breast cancer: Current options and future perspectives",

abstract = "Endocrine resistance remains a challenge and an unmet need for managing hormone receptor-positive breast cancer. The mechanisms of endocrine resistance are multifaceted and are likely to evolve over time following various single or combination therapies. The purpose of this review article is to provide general understanding of molecular basis of endocrine resistance of breast cancer and to offer comprehensive review on current treatment options and potential new treatment strategies for endocrine resistant breast cancers. Last but not the least, we discuss current challenges and future directions for management of endocrine resistant breast cancers.",

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author = "Liu, {Chun Yu} and Wu, {Chia Yun} and Karineh Petrossian and Huang, {Tzu Ting} and Tseng, {Ling Ming} and Shiuan Chen",

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T2 - Current options and future perspectives

AU - Liu, Chun Yu

AU - Wu, Chia Yun

AU - Petrossian, Karineh

AU - Huang, Tzu Ting

AU - Tseng, Ling Ming

AU - Chen, Shiuan

PY - 2017/9

Y1 - 2017/9

N2 - Endocrine resistance remains a challenge and an unmet need for managing hormone receptor-positive breast cancer. The mechanisms of endocrine resistance are multifaceted and are likely to evolve over time following various single or combination therapies. The purpose of this review article is to provide general understanding of molecular basis of endocrine resistance of breast cancer and to offer comprehensive review on current treatment options and potential new treatment strategies for endocrine resistant breast cancers. Last but not the least, we discuss current challenges and future directions for management of endocrine resistant breast cancers.

AB - Endocrine resistance remains a challenge and an unmet need for managing hormone receptor-positive breast cancer. The mechanisms of endocrine resistance are multifaceted and are likely to evolve over time following various single or combination therapies. The purpose of this review article is to provide general understanding of molecular basis of endocrine resistance of breast cancer and to offer comprehensive review on current treatment options and potential new treatment strategies for endocrine resistant breast cancers. Last but not the least, we discuss current challenges and future directions for management of endocrine resistant breast cancers.

KW - Breast cancer

KW - Endocrine resistance

KW - Estrogen receptor

KW - Hormone receptor

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U2 - 10.1016/j.jsbmb.2017.07.001

DO - 10.1016/j.jsbmb.2017.07.001

M3 - Review article

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SN - 0960-0760

VL - 172

SP - 166

EP - 175

JO - Journal of Steroid Biochemistry and Molecular Biology

JF - Journal of Steroid Biochemistry and Molecular Biology

ER -

Treatment for the endocrine resistant breast cancer: Current options and future perspectives

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