The use of polymer-based nanoparticles and nanostructured materials in treatment and diagnosis of cardiovascular diseases: Recent advances and emerging designs

Yen Jen Wang, Mikael Larsson, Wei Ting Huang, Shih Hwa Chiou, Stephen J. Nicholls, Jui-I Chao, Dean-Mo LIu*

*此作品的通信作者

研究成果: Review article同行評審

47 引文 斯高帕斯(Scopus)

摘要

This review summarizes important advances in polymer-based nanotechnologies for the treatment and diagnosis of cardiovascular diseases, focusing on nanoparticles and nanostructured materials/devices. The current state of the art and design parameters are discussed with the aim of providing a source of information that can aid in the development of new treatments by bridging between materials development, preclinical, and clinical trials. This is highly relevant as cardiovascular diseases remain a leading cause of death worldwide and as current treatments burden the healthcare systems with great costs. Different strategies, from targeting theranostic nanocarriers, to dual-drug depot systems, injectable cell scaffolds, and LDL acceptors are treated. The review ends with a concluding outlook on the possibilities and challenges presented to polymer-based nanotechnologies in cardiovascular disease therapy.

原文English
頁(從 - 到)153-178
頁數26
期刊Progress in Polymer Science
57
DOIs
出版狀態Published - 1 6月 2016

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