We show that hepatitis C virus (HCV) p7 protein forms ion channels in black lipid membranes. HCV p7 ion channels are inhibited by long-alkyl-chain iminosugar derivatives, which have antiviral activity against the HCV surrogate bovine viral diarrhea virus. HCV p7 presents a potential target for antiviral therapy.
|頁（從 - 到）||6104-6108|
|期刊||Proceedings of the National Academy of Sciences of the United States of America|
|出版狀態||Published - 13 5月 2003|