The distinct pairing sequence of liver cell and fibroblast on cell-cell fusion platform

Shih Mo Yang, Chun Yen Lin, Shilpa Sivashankar, Srinivasu Valagerahally Puttaswamy, Yen Ta Lu, Hwan You Chang, Long Hsu, Cheng Hsien Liu

研究成果: Conference contribution同行評審

摘要

Recently we are developing the cell-cell fusion platform which has a potential to modify cell behavior for degenerative diseases. We present a cell-cell pairing platform to trap and pair mobile HepG2 liver cells and 3T3 fibroblast cells. A 10μm×20μm metal electrode is placed precisely inside a lateral cavity. The lateral cavity design bends the electric field and enlarges the positive dielectrophoresis force. Besides, the structure provides a shelter function to diminish the damage of direct flow shear stress acting on trapped cells. Finally, we demonstrate the distinct liver and fibroblast cells pairing sequence for the future application of cell-cell fusion.

原文English
主出版物標題15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
頁面849-851
頁數3
出版狀態Published - 1 12月 2011
事件15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
持續時間: 2 10月 20116 10月 2011

出版系列

名字15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
2

Conference

Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
國家/地區United States
城市Seattle, WA
期間2/10/116/10/11

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