TY - JOUR
T1 - The core of hepatitis C virus pathogenesis
AU - Kao, C. Cheng
AU - Yi, Guanghui
AU - Huang, Hsuan Cheng
N1 - Publisher Copyright:
© 2016 Elsevier B.V. All rights reserved.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Capsid proteins form protective shells around viral genomes and mediate viral entry. However, many capsid proteins have additional and important roles for virus infection and in modulating cellular response to infection, with important consequences on pathogenesis. Infection by the Hepatitis C virus (HCV) can lead to liver steatosis, cirrhosis, and hepatocellular carcinoma. Herein, we focus on the role in pathogenesis of Core, the capsid protein of the HCV.
AB - Capsid proteins form protective shells around viral genomes and mediate viral entry. However, many capsid proteins have additional and important roles for virus infection and in modulating cellular response to infection, with important consequences on pathogenesis. Infection by the Hepatitis C virus (HCV) can lead to liver steatosis, cirrhosis, and hepatocellular carcinoma. Herein, we focus on the role in pathogenesis of Core, the capsid protein of the HCV.
UR - http://www.scopus.com/inward/record.url?scp=84964647174&partnerID=8YFLogxK
U2 - 10.1016/j.coviro.2016.01.009
DO - 10.1016/j.coviro.2016.01.009
M3 - Review article
C2 - 26851516
AN - SCOPUS:84964647174
SN - 1879-6257
VL - 17
SP - 66
EP - 73
JO - Current Opinion in Virology
JF - Current Opinion in Virology
ER -
