Taxane-induced peripheral neuropathy: Objective and subjective comparison between paclitaxel and docetaxel in patients with breast cancer

Ya Ning Chan, You Wun Jheng, Pei Ju Wang, Chin Yau Chen, Ming Wei Lin, Ya Jung Wang*

*此作品的通信作者

研究成果: Article同行評審

7 引文 斯高帕斯(Scopus)

摘要

BACKGROUND: Taxane-induced peripheral neuropathy (TIPN) is caused by the neurotoxicity of paclitaxel and docetaxel, but the differences between paclitaxel- and docetaxel-induced peripheral neuropathy are understudied. OBJECTIVES: The purpose of this study is to compare TIPN between docetaxel and paclitaxel in patients with breast cancer and to examine the consistency of measuring TIPN between researchers and patients. METHODS: Secondary data were analyzed from a cross-sectional study that included 64 patients with breast cancer from two teaching hospitals in Taiwan. Objective and subjective TIPN were measured. FINDINGS: Results indicated significant differences in objective TIPN, sensory sum score, and motor sum score between groups. No significant difference was detected in subjective TIPN between groups.

原文English
頁(從 - 到)494-501
頁數8
期刊Clinical Journal of Oncology Nursing
23
發行號5
DOIs
出版狀態Published - 10月 2019

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