Surgical resection combined with chemotherapy can help achieve better outcomes in patients with primary colonic lymphoma

Yi Ling Lai, Jen Kou Lin, Wen Yih Liang, Yu Chung Huang, Shih Ching Chang*

*此作品的通信作者

研究成果: Review article同行評審

33 引文 斯高帕斯(Scopus)

摘要

Background and Objectives The colon is a rare location for gastrointestinal non-Hodgkin's lymphoma. We retrospectively analyzed the demographic data of patients with colonic lymphoma and the possible prognostic factors of the disease. Methods We studied data obtained from 6,944 patients and performed a retrospective review of patients with primary colonic lymphoma (PCL) by using a pathology registry database. We employed well-established and accepted diagnostic criteria and clinical staging method. Results Twenty-nine patients (19 men; 10 women) were diagnosed with PCL. The cecum was the most common tumor location (14/29 patients), and 17 cases (17/29) showed diffuse large-B-cell lymphomas. Four patients died of sepsis within 30 days of an emergency surgery for perforation of intestine. Two-thirds of the patients were in the early disease stages (stages I and II). The overall 5-year survival rate was 47.3%. Disease stage was not a prognostic factor for survival. The overall 5-year survival rate in patients treated with surgery followed by chemotherapy was statistically significant as compared to that in the patients treated with chemotherapy alone. Conclusion PCL is a rare malignancy of the gastrointestinal tract, and surgical resection should be considered a part of the standard treatment to achieve a better outcome.

原文English
頁(從 - 到)265-268
頁數4
期刊Journal of Surgical Oncology
104
發行號3
DOIs
出版狀態Published - 1 9月 2011

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