Surgical Outcomes in Resected Non-small Cell Lung Cancer ≤ 1 cm in Diameter

Bing Yen Wang, Jung Jyh Hung, Wen Juei Jeng, Wen Hu Hsu, Chih Cheng Hsieh, Min Hsiung Huang, Biing Shiun Huang, Jung Sen Liu, Yu Chung Wu*


研究成果: Article同行評審

5 引文 斯高帕斯(Scopus)


Background: The goal of this study was to investigate the prognostic factors and patterns of recurrence in patients with resected non-small cell lung cancer (NSCLC) ≤ 1 cm in diameter. Methods: We conducted a retrospective review of the clinicopathological characteristics of 71 patients with NSCLC ≤ 1 cm in diameter in Taipei Veterans General Hospital between 1982 and 2007. Overall survival and its predictors were analyzed. Results: Median follow-up time of the 71 patients was 33.3 months. Complete resection was performed in 68 patients (95.8%) with stage I disease. The 5- and 10-year overall survival rates of patients who underwent complete resections were 81.7% and 44.9%, respectively. There was tumor recurrence in 6 (8.8%) of these 68 patients. Five (9.3%) of 54 patients who underwent standard resection experienced tumor recurrence, but only 1 (7.1%) of 14 patients who received sublobar resection had recurrent disease. The difference was not statistically significant (p = 0.569). Multivariate analysis revealed that sublobar resection (hazard ratio, 5.00; 95% confidence interval, 1.28-20.00; p = 0.020) was a significant predictor for worse overall survival. Conclusion: Survival in patients with NSCLC £ 1 cm in diameter is satisfactory. Sublobar resection, performed in patients unfit for standard resection, is a poor prognostic factor for overall survival.

頁(從 - 到)308-313
期刊Journal of the Chinese Medical Association
出版狀態Published - 6月 2010


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