TY - JOUR
T1 - Surgical management of primary retroperitoneal sarcoma
AU - Wang, Tai Yuan
AU - Lo, Su Shun
AU - Su, Cheng Hsi
AU - Wu, Chew Wun
AU - Lui, Wing Yiu
PY - 1996/9
Y1 - 1996/9
N2 - Background. Retroperitoneal sarcoma is a rare and challenging group of diseases for surgeons, characterized by extensive growth and high recurrent rate. We analyzed data from our patients to identify the factors of survival. Methods. From 1971 to 1993, medical records of 40 patients with primary retroperitoneal sarcoma were reviewed. Clinical factors including age, sex, tumor size, histopathology, type of operation, disease-free interval, and number of operation were collected to correlate with patient's survival. Results. Most patients presented with huge abdominal mass. There were 22 liposarcomas, 8 leiomyosarcomas, 5 malignant fibrous histiocytomas, 2 fibrosarcomas, 2 malignant mesenchymomas and one rhabdomyosarcoma. Twenty-eight patients received complete resection and 12 had incomplete resection. The group with complete resection showed a better survival than incomplete resection group (p =0.0001). Nineteen patients with complete resection had tumor recurrence. The recurrent rate was 68%. Patients having been disease-free for more than 12 months showed to have better survival than those less than 12 months (p =0.005). Aggressive surgical resection was done in case of tumor recurrence. Patients who received more than 2 (≥3) operations also showed a better survival than those with less than 2 operations (p =0.0247). Conclusions. Complete surgical resection and aggressive repeated surgical intervention are the most effective treatment modality for better survival in patients with retroperitoneal sarcoma.
AB - Background. Retroperitoneal sarcoma is a rare and challenging group of diseases for surgeons, characterized by extensive growth and high recurrent rate. We analyzed data from our patients to identify the factors of survival. Methods. From 1971 to 1993, medical records of 40 patients with primary retroperitoneal sarcoma were reviewed. Clinical factors including age, sex, tumor size, histopathology, type of operation, disease-free interval, and number of operation were collected to correlate with patient's survival. Results. Most patients presented with huge abdominal mass. There were 22 liposarcomas, 8 leiomyosarcomas, 5 malignant fibrous histiocytomas, 2 fibrosarcomas, 2 malignant mesenchymomas and one rhabdomyosarcoma. Twenty-eight patients received complete resection and 12 had incomplete resection. The group with complete resection showed a better survival than incomplete resection group (p =0.0001). Nineteen patients with complete resection had tumor recurrence. The recurrent rate was 68%. Patients having been disease-free for more than 12 months showed to have better survival than those less than 12 months (p =0.005). Aggressive surgical resection was done in case of tumor recurrence. Patients who received more than 2 (≥3) operations also showed a better survival than those with less than 2 operations (p =0.0247). Conclusions. Complete surgical resection and aggressive repeated surgical intervention are the most effective treatment modality for better survival in patients with retroperitoneal sarcoma.
KW - Complete resection
KW - Disease-free interval
KW - Retroperitoneal sarcoma
UR - http://www.scopus.com/inward/record.url?scp=28244474181&partnerID=8YFLogxK
M3 - Article
C2 - 8940789
AN - SCOPUS:28244474181
SN - 1726-4901
VL - 58
SP - 177
EP - 182
JO - Journal of the Chinese Medical Association
JF - Journal of the Chinese Medical Association
IS - 3
ER -