Surface modification of materials by plasma process and UV-induced grafted polymerization for biomedical applications

Surface modification using plasma treated and graft polymerization is versatile process, with systems on the market capable of treating everything from polymer, metal, and ceramic substrates. The major advantage is that the modification is caused no substrate damage or bulk property changes. This is a very effective method to modify the surfaces of biomaterials to achieve desired physical or mechanical properties, or to induce a specific response when the device is placed in the body. They offer attractive possibilities for developing new biomaterials and for improving the performance of existing materials and devices. Hence, in this review, we describe the application of plasma treatment and graft polymerization on biomaterials field. The various applications are discussed in the following: (1) easy stripped-off wound dressing, (2) porous three-dimensional temporary scaffolds, (3) quartz crystal microbalance (QCM) base biosensors, and (4) covalent immobilization of glucose oxidase onto inorganic substrates.