Suicide risk in patients with migraine and comorbid fibromyalgia

Hung Yu Liu, Jong Ling Fuh, Yung Yang Lin, Wei Ta Chen, Shuu Jiun Wang*


研究成果: Article同行評審

21 引文 斯高帕斯(Scopus)


Objectives: To identify the frequency, clinical effects, and suicide risk in comorbid fibromyalgia (FM) among patients with migraine. Methods: We surveyed patients with migraine who attended a headache clinic. All patients completed questionnaires containing demographics, headache profiles based on the International Classification of Headache Disorders, 2nd edition, FM questionnaires based on the modified 2010 American College of Rheumatology preliminary diagnostic criteria, Migraine Disability Assessment, Hospital Anxiety and Depression Scale, and Pittsburgh Sleep Quality Index. Suicide risk was evaluated by self-report of lifetime suicidal ideation and attempts. Results: Of the 1,318 recruited patients with migraine (aged 42.6 ± 12.7 years; female/male 4.5), 10.1% (aged 44.3 ± 12.6 years; female/male 7.9) had comorbidity of FM. Patients with migraine and comorbid FM had higher headache frequency and headache-related disability, poor sleep quality, and were more depressed/anxious than those with migraine only (p < 0.001). Suicidal ideation and attempts were reported in 27.3% and 6.9% of patients with migraine, respectively, and were higher in patients with comorbid FM than in those without (ideation: 58.3% vs 24%; attempt: 17.6% vs 5.7%; p < 0.001). In addition, comorbidity of FM was associated with a higher suicide risk in 3 different migraine subgroups, i.e., migraine without aura, migraine with aura, and chronic migraine. After controlling for covariates, comorbidity of FM remained as a predictor of suicidal ideation and attempts (odds ratio 2.61 and 1.99, respectively, p < 0.05) in patients with migraine. Conclusions: Comorbidity with FM is associated with a high suicide risk in patients with migraine.

頁(從 - 到)1017-1023
出版狀態Published - 22 9月 2015


深入研究「Suicide risk in patients with migraine and comorbid fibromyalgia」主題。共同形成了獨特的指紋。