摘要
A reflective light-scattering (RLS) microscope with structured illumination (SI) provides subdiffraction resolution and improves the image quality of gold nanoparticles in biological systems. The three-dimensional (3D)-structured pattern is rapidly and precisely controlled with a spatial light modulator and scrambled at the conjugate image plane to increase spatial incoherence. The reconstructed SI-RLS image of 100nm gold nanoparticles reveals lateral and axial resolutions of approximately 117 and 428nm. We present a high-resolution image of gold nanoparticles inside a HeLa cell, with improved contrast.
| 原文 | English |
|---|---|
| 頁（從 - 到） | 4773-4775 |
| 頁數 | 3 |
| 期刊 | Optics Letters |
| 卷 | 36 |
| 發行號 | 24 |
| DOIs | |
| 出版狀態 | Published - 15 12月 2011 |