Structural Insights into the Free-Standing Condensation Enzyme SgcC5 Catalyzing Ester-Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027

Chin-Yuan Chang, Jeremy R. Lohman, Tingting Huang, Karolina Michalska, Lance Bigelow, Jeffrey D. Rudolf, Robert Jedrzejczak, Xiaohui Yan, Ming Ma, Gyorgy Babnigg, Andrzej Joachimiak, George N. Phillips, Ben Shen^*