SPIKES: Identification of physicochemical properties of spike proteins across diverse host species of SARS-CoV-2

Srinivasulu Yerukala Sathipati*, Ming Ju Tsai, Tonia Carter, Sanjay K. Shukla, Shinn Ying Ho

*此作品的通信作者

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摘要

We describe a protocol to identify physicochemical properties using amino acid sequences of spike (S) proteins of SARS-CoV-2. We present an S protein prediction technique named SPIKES, incorporating an inheritable bi-objective combinatorial genetic algorithm to determine the host species specificity. This protocol addresses the S protein amino acid sequence data collection, preprocessing, methodology, and analysis. For complete details on the use and execution of this protocol, please refer to Yerukala Sathipati et al. (2022).

原文English
文章編號101460
期刊STAR Protocols
3
發行號3
DOIs
出版狀態Published - 16 9月 2022

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