Simulation of axon activation by electrical stimulation applying alternating-direction-implicit finite-difference time-domain method

T.m. Choi*, Shu Hai Sun

*此作品的通信作者

研究成果: Article同行評審

6 引文 斯高帕斯(Scopus)

摘要

In a typical approach to model electrical stimulation of an axon, a cable model equivalent to an axon was placed in a simple homogeneous medium. An electrode was used to induce an excitation to stimulate the cable model, and then the transmembrane potentials and the ionic currents in the cable model in temporal domain were observed. Unfortunately, this simulation approach is not realistic since inhomogeneous tissues near the axon is not considered. In this paper, the alternating-direction-implicit finite-difference time-domain (ADI-FDTD) method is coupled with the equivalent model of a membrane (the Hodgkin-Huxley model), and a novel simulation scheme is developed to predict axon activation. By testing axon activation with current excitation, the simulation results show the new method is useful for simulating axon activation.

原文English
文章編號6136610
頁(從 - 到)639-642
頁數4
期刊IEEE Transactions on Magnetics
48
發行號2
DOIs
出版狀態Published - 1 二月 2012

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