TY - JOUR
T1 - Silica-Supported Cu Nanoparticle Catalysts for Alkyne Semihydrogenation
T2 - Effect of Ligands on Rates and Selectivity
AU - Fedorov, Alexey
AU - Liu, Hsuch-Ju
AU - Lo, Hung Kun
AU - Copéret, Christophe
PY - 2016/12/21
Y1 - 2016/12/21
N2 - Narrowly dispersed, silica-supported Cu nanoparticles (ca. 2 nm) prepared via surface organometallic chemistry from a mesityl complex [Cu5Mes5] are highly active for the hydrogenation of a broad range of alkynes. High-throughput experimentation allows for identifying the optimal ligand and reaction conditions to turn these supported Cu nanoparticles into highly chemo- and stereoselective catalysts for the preparation of Z-olefins (overall, 23 examples). For instance, PCy3-modified Cu nanoparticles semihydrogenate 1-phenyl-1-propyne to cis-β-methylstyrene (20 bar H2, 40 °C) with turnover number and turnover frequency of ca. 540 and 1.9 min-1, respectively, and with 94% selectivity at full conversion.
AB - Narrowly dispersed, silica-supported Cu nanoparticles (ca. 2 nm) prepared via surface organometallic chemistry from a mesityl complex [Cu5Mes5] are highly active for the hydrogenation of a broad range of alkynes. High-throughput experimentation allows for identifying the optimal ligand and reaction conditions to turn these supported Cu nanoparticles into highly chemo- and stereoselective catalysts for the preparation of Z-olefins (overall, 23 examples). For instance, PCy3-modified Cu nanoparticles semihydrogenate 1-phenyl-1-propyne to cis-β-methylstyrene (20 bar H2, 40 °C) with turnover number and turnover frequency of ca. 540 and 1.9 min-1, respectively, and with 94% selectivity at full conversion.
UR - http://www.scopus.com/inward/record.url?scp=85006860838&partnerID=8YFLogxK
U2 - 10.1021/jacs.6b10817
DO - 10.1021/jacs.6b10817
M3 - Article
AN - SCOPUS:85006860838
SN - 0002-7863
VL - 138
SP - 16502
EP - 16507
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 50
ER -