Sequential [3 + 2] and [4 + 2] cycloadditions for stereoselective synthesis of a novel polyheterocyclic scaffold

Qing Lu, Xin Huang, Gonghua Song, Chung-Ming Sun, Jerry P. Jasinski, Amanda C. Keeley, Wei Zhang*

*此作品的通信作者

研究成果: Article同行評審

26 引文 斯高帕斯(Scopus)

摘要

A strategy of combining [3 + 2] cycloaddition and intramolecular Diels-Alder reaction is developed for the synthesis of a novel polycyclic scaffold with skeletal and substitutional diversities. Intermediates generated from stereoselective [3 + 2] cycloaddition of azomethine ylides and maleimides were derivatized for intramolecular Diels-Alder reaction of furan to form highly condensed heterocyclic products as racemic single diastereomers.

原文English
頁(從 - 到)350-355
頁數6
期刊ACS Combinatorial Science
15
發行號7
DOIs
出版狀態Published - 8 7月 2013

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