Seizure after reversal of benzodiazepine treatment with flumazenil: A report of two cases

K. O. Ng; G. J. Tang; S. S. Hseu; C. H. Hsing; T. Y. Lee

Seizure after reversal of benzodiazepine treatment with flumazenil: A report of two cases

K. O. Ng, G. J. Tang^*, S. S. Hseu, C. H. Hsing, T. Y. Lee

^*此作品的通信作者

醫務管理研究所

研究成果: Article › 同行評審

3 引文斯高帕斯（Scopus）

摘要

Two patients developed seizure immediately after flumazenil administration that aimed to reverse the prolonged sedative effect of diazepam. The use of benzodiazepine for sedation in ICU may mask valuable information relevant to an ongoing pathological change. The seizure in our patients seemed most likely to result from septic ence phalopathy which was unmasked by flumazenil. However, flumazenil has the potential to provoke seizure and should be used with caution.

原文	English
頁（從 - 到）	383-387
頁數	5
期刊	Chinese Medical Journal (Taipei)
卷	53
發行號	6
出版狀態	Published - 1994

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title = "Seizure after reversal of benzodiazepine treatment with flumazenil: A report of two cases",

abstract = "Two patients developed seizure immediately after flumazenil administration that aimed to reverse the prolonged sedative effect of diazepam. The use of benzodiazepine for sedation in ICU may mask valuable information relevant to an ongoing pathological change. The seizure in our patients seemed most likely to result from septic ence phalopathy which was unmasked by flumazenil. However, flumazenil has the potential to provoke seizure and should be used with caution.",

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AU - Ng, K. O.

AU - Tang, G. J.

AU - Hseu, S. S.

AU - Hsing, C. H.

AU - Lee, T. Y.

PY - 1994

Y1 - 1994

N2 - Two patients developed seizure immediately after flumazenil administration that aimed to reverse the prolonged sedative effect of diazepam. The use of benzodiazepine for sedation in ICU may mask valuable information relevant to an ongoing pathological change. The seizure in our patients seemed most likely to result from septic ence phalopathy which was unmasked by flumazenil. However, flumazenil has the potential to provoke seizure and should be used with caution.

AB - Two patients developed seizure immediately after flumazenil administration that aimed to reverse the prolonged sedative effect of diazepam. The use of benzodiazepine for sedation in ICU may mask valuable information relevant to an ongoing pathological change. The seizure in our patients seemed most likely to result from septic ence phalopathy which was unmasked by flumazenil. However, flumazenil has the potential to provoke seizure and should be used with caution.

KW - anesthesia

KW - flumazenil

KW - seizure

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SP - 383

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JO - Chinese Medical Journal (Taipei)

JF - Chinese Medical Journal (Taipei)

IS - 6

ER -

Seizure after reversal of benzodiazepine treatment with flumazenil: A report of two cases

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