Role of sinus node during atrial fibrillation: A novel insight from regional frequency analysis

H. W. Tso*, T. Kao, Y. J. Lin, C. T. Tai, S. A. Chen

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

The sinus node (SAN) is demonstrated to play a role in the genesis and the perpetuation of atrial fibrillation (AF). The sinus activation during AF is difficult to analyze with conventional electrogram recordings. The purpose of this study was to investigate the atrial substrate characteristics near the sinus node (SAN) during sinus rhythm (SR), ongoing AF and before AF termination according to the frequency analysis compared to the rest of the right atrium (RRA). The present study included 6 patients with paroxysmal AF underwent noncontact mapping for the right atrium (RA). After subtraction of QRS-T complex, regional frequency distribution was obtained from the signals of 256-equally distribution mapping site for three situations. The dominant frequency (DF), power amplitude (MP), and organization index(OI) of DF between SAN and RRA during AF were similar (p>0.1). However, the DF of SAN area became lower (p<0.001), the power amplitude of local spectra (p<0.005) was higher, and more organization (P<0.001) compared to RRA before termination of AF. In conclusion, atrial substrate around the SAN is characterized by slower atrial activity compared to the rest of the right atrium during termination of AF. The frequency analysis showed that the DF around SAN area during AF termination was similar to during SR, suggesting that the sinus automaticity was preserved with local entrance block from the rest of the atrium.

原文English
主出版物標題Computers in Cardiology, 2005
頁面65-68
頁數4
DOIs
出版狀態Published - 2005
事件Computers in Cardiology, 2005 - Lyon, France
持續時間: 25 9月 200528 9月 2005

出版系列

名字Computers in Cardiology
32
ISSN(列印)0276-6574

Conference

ConferenceComputers in Cardiology, 2005
國家/地區France
城市Lyon
期間25/09/0528/09/05

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