Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand

Bruce Y. Lee; Tina Marie Assi; Korngamon Rookkapan; Diana L. Connor; Jayant Rajgopal; Vorasith Sornsrivichai; Shawn T. Brown; Joel S. Welling; Bryan A. Norman; Sheng-I Chen; Rachel R. Bailey; Ann E. Wiringa; Angela R. Wateska; Anirban Jana; Willem G. Van Panhuis; Donald S. Burke

doi:10.1016/j.vaccine.2011.03.013

Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand

Bruce Y. Lee^*, Tina Marie Assi, Korngamon Rookkapan, Diana L. Connor, Jayant Rajgopal, Vorasith Sornsrivichai, Shawn T. Brown, Joel S. Welling, Bryan A. Norman, Sheng-I Chen, Rachel R. Bailey, Ann E. Wiringa, Angela R. Wateska, Anirban Jana, Willem G. Van Panhuis, Donald S. Burke

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工業工程與管理學系

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38 引文斯高帕斯（Scopus）

摘要

Introduced to minimize open vial wastage, single-dose vaccine vials require more storage space and therefore may affect vaccine supply chains (i.e., the series of steps and processes involved in distributing vaccines from manufacturers to patients). We developed a computational model of Thailand's Trang province vaccine supply chain to analyze the effects of switching from a ten-dose measles vaccine presentation to each of the following: a single-dose measles-mumps-rubella vaccine (which Thailand is currently considering) or a single-dose measles vaccine. While the Trang province vaccine supply chain would generally have enough storage and transport capacity to accommodate the switches, the added volume could push some locations' storage and transport space utilization close to their limits. Single-dose vaccines would allow for more precise ordering and decrease open vial waste, but decrease reserves for unanticipated demand. Moreover, the added disposal and administration costs could far outweigh the costs saved from preventing open vial wastage.

原文	English
頁（從 - 到）	3811-3817
頁數	7
期刊	Vaccine
卷	29
發行號	21
DOIs	https://doi.org/10.1016/j.vaccine.2011.03.013
出版狀態	Published - 12 5月 2011

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Lee, B. Y., Assi, T. M., Rookkapan, K., Connor, D. L., Rajgopal, J., Sornsrivichai, V., Brown, S. T., Welling, J. S., Norman, B. A., Chen, S.-I., Bailey, R. R., Wiringa, A. E., Wateska, A. R., Jana, A., Van Panhuis, W. G., & Burke, D. S. (2011). Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand. Vaccine, 29(21), 3811-3817. https://doi.org/10.1016/j.vaccine.2011.03.013

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title = "Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand",

abstract = "Introduced to minimize open vial wastage, single-dose vaccine vials require more storage space and therefore may affect vaccine supply chains (i.e., the series of steps and processes involved in distributing vaccines from manufacturers to patients). We developed a computational model of Thailand's Trang province vaccine supply chain to analyze the effects of switching from a ten-dose measles vaccine presentation to each of the following: a single-dose measles-mumps-rubella vaccine (which Thailand is currently considering) or a single-dose measles vaccine. While the Trang province vaccine supply chain would generally have enough storage and transport capacity to accommodate the switches, the added volume could push some locations' storage and transport space utilization close to their limits. Single-dose vaccines would allow for more precise ordering and decrease open vial waste, but decrease reserves for unanticipated demand. Moreover, the added disposal and administration costs could far outweigh the costs saved from preventing open vial wastage.",

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author = "Lee, {Bruce Y.} and Assi, {Tina Marie} and Korngamon Rookkapan and Connor, {Diana L.} and Jayant Rajgopal and Vorasith Sornsrivichai and Brown, {Shawn T.} and Welling, {Joel S.} and Norman, {Bryan A.} and Sheng-I Chen and Bailey, {Rachel R.} and Wiringa, {Ann E.} and Wateska, {Angela R.} and Anirban Jana and {Van Panhuis}, {Willem G.} and Burke, {Donald S.}",

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Lee, BY, Assi, TM, Rookkapan, K, Connor, DL, Rajgopal, J, Sornsrivichai, V, Brown, ST, Welling, JS, Norman, BA, Chen, S-I, Bailey, RR, Wiringa, AE, Wateska, AR, Jana, A, Van Panhuis, WG & Burke, DS 2011, 'Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand', Vaccine, 卷 29, 編號 21, 頁 3811-3817. https://doi.org/10.1016/j.vaccine.2011.03.013

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AU - Assi, Tina Marie

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AU - Rajgopal, Jayant

AU - Sornsrivichai, Vorasith

AU - Brown, Shawn T.

AU - Welling, Joel S.

AU - Norman, Bryan A.

AU - Chen, Sheng-I

AU - Bailey, Rachel R.

AU - Wiringa, Ann E.

AU - Wateska, Angela R.

AU - Jana, Anirban

AU - Van Panhuis, Willem G.

AU - Burke, Donald S.

PY - 2011/5/12

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N2 - Introduced to minimize open vial wastage, single-dose vaccine vials require more storage space and therefore may affect vaccine supply chains (i.e., the series of steps and processes involved in distributing vaccines from manufacturers to patients). We developed a computational model of Thailand's Trang province vaccine supply chain to analyze the effects of switching from a ten-dose measles vaccine presentation to each of the following: a single-dose measles-mumps-rubella vaccine (which Thailand is currently considering) or a single-dose measles vaccine. While the Trang province vaccine supply chain would generally have enough storage and transport capacity to accommodate the switches, the added volume could push some locations' storage and transport space utilization close to their limits. Single-dose vaccines would allow for more precise ordering and decrease open vial waste, but decrease reserves for unanticipated demand. Moreover, the added disposal and administration costs could far outweigh the costs saved from preventing open vial wastage.

AB - Introduced to minimize open vial wastage, single-dose vaccine vials require more storage space and therefore may affect vaccine supply chains (i.e., the series of steps and processes involved in distributing vaccines from manufacturers to patients). We developed a computational model of Thailand's Trang province vaccine supply chain to analyze the effects of switching from a ten-dose measles vaccine presentation to each of the following: a single-dose measles-mumps-rubella vaccine (which Thailand is currently considering) or a single-dose measles vaccine. While the Trang province vaccine supply chain would generally have enough storage and transport capacity to accommodate the switches, the added volume could push some locations' storage and transport space utilization close to their limits. Single-dose vaccines would allow for more precise ordering and decrease open vial waste, but decrease reserves for unanticipated demand. Moreover, the added disposal and administration costs could far outweigh the costs saved from preventing open vial wastage.

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Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand

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