摘要
Retinoic acid plays a key role in the development and function of the immune system; however, the contribution of each of the three retinoic acid receptors (RARs) to the T cell immune response is not yet well understood. Of these receptors, both RARα and RARγ are expressed in T lymphocytes. While possible functional redundancy thus complicates understanding of the role of each receptor in T cells, emerging data suggest that RARα and RARγ function differently in thymocyte development and that RARγ is required for both primary and secondary CD8+ T cell immune responses.
原文 | English |
---|---|
頁(從 - 到) | 2-7 |
頁數 | 6 |
期刊 | Seminars in Immunology |
卷 | 21 |
發行號 | 1 |
DOIs | |
出版狀態 | Published - 2月 2009 |