Regulation of CD8+ T cell functions by RARγ

Claire Gordy, Ivan Dzhagalov, You Wen He*

*此作品的通信作者

研究成果: Review article同行評審

13 引文 斯高帕斯(Scopus)

摘要

Retinoic acid plays a key role in the development and function of the immune system; however, the contribution of each of the three retinoic acid receptors (RARs) to the T cell immune response is not yet well understood. Of these receptors, both RARα and RARγ are expressed in T lymphocytes. While possible functional redundancy thus complicates understanding of the role of each receptor in T cells, emerging data suggest that RARα and RARγ function differently in thymocyte development and that RARγ is required for both primary and secondary CD8+ T cell immune responses.

原文English
頁(從 - 到)2-7
頁數6
期刊Seminars in Immunology
21
發行號1
DOIs
出版狀態Published - 2月 2009

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