Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

Priscilla Cheung, Jordi Xiol, Michael T. Dill, Wei Chien Yuan, Riccardo Panero, Jatin Roper, Fernando G. Osorio, Dejan Maglic, Qi Li, Basanta Gurung, Raffaele A. Calogero, Ömer H. Yilmaz, Junhao Mao, Fernando D. Camargo*

*此作品的通信作者

研究成果: Article同行評審

60 引文 斯高帕斯(Scopus)

摘要

Hippo inhibition reprograms intestinal stem cells (ISCs) to a wound-healing-like cell state that can be induced to suppress tumorigenesis in human and mouse metastatic colorectal cancer.

原文English
頁(從 - 到)590-604.e9
期刊Cell Stem Cell
27
發行號4
DOIs
出版狀態Published - 1 10月 2020

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