Recent advances in D-A-D based Pdots with NIR-II fluorescence for deep-tissue imaging

Partha Chowdhury, Yang Hsiang Chan*

*此作品的通信作者

研究成果: Review article同行評審

15 引文 斯高帕斯(Scopus)

摘要

In recent years, semiconducting polymer-based nanoparticles (Pdots) emitting in the second near-infrared window (NIR-II, 1000-1700 nm) have become a promising type of ultrabright fluorescence probe benefitting from numerous advantages in the NIR-II region, including reduced photon scattering, minimal tissue autofluorescence, and deep-tissue penetration. Among the diverse types of NIR-II fluorescent Pdots, donor-acceptor-donor (D-A-D)-based Pdots exhibit superior properties over others, especially for their high fluorescent brightness and excellent photostability. This mini-review article focuses on the recent development of D-A-D based Pdots emitting in the NIR-II window and their diverse applications in deep-tissue in vivo imaging. Finally, an outlook is given for the future designs of bright NIR-II D-A-D Pdots.

原文English
頁(從 - 到)702-719
頁數18
期刊Molecular Systems Design and Engineering
7
發行號7
DOIs
出版狀態Published - 8 4月 2022

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