Rapid Prototyping of an Open-Surface Microfluidic Platform Using Wettability-Patterned Surfaces Prepared by an Atmospheric-Pressure Plasma Jet

She Ting Wu, Chen Yu Huang, Chih Chiang Weng, Chia-Chih Chang, Bor-Ran Li*, Chain-Shu Hsu

*此作品的通信作者

研究成果: Article同行評審

13 引文 斯高帕斯(Scopus)

摘要

Open-surface microfluidics is promising in terms of enabling economical and rapid biochemical analysis for addressing challenges associated with medical diagnosis and food safety. To this end, we present a simple and economical approach to develop an open-surface microfluidic platform suitable for facile liquid transport and mixing. Customizable patterns with tailored wettability are deposited using a plasma-assisted deposition technique under atmospheric pressure. The flow of the dispensed liquid is driven by gravity, and the tilting angle of the device determines the extent of mixing. First, a hexamethyldisiloxane film was deposited to create hydrophobic patterns on glass, and then, hydrophilic acrylic acid was deposited by a patterned cardboard mask to construct a channel suitable for forming channels to transport aqueous liquids without the need of an external energy input; the liquid can be confined to designated pathways. Several designs including Y-junctions, serpentine-shaped patterns, splitting channels, and concentration gradient generation patterns are presented. The proposed method can spatially pattern a surface with a hydrophobic/hydrophilic area, which can function as a microfluidic channel, and the surface can be applied in microfluidic devices with other types of substrates.

原文English
頁(從 - 到)16292-16299
頁數8
期刊ACS Omega
4
發行號15
DOIs
出版狀態Published - 8 10月 2019

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