TY - JOUR
T1 - Raman spectroscopic study of concentration dynamics in glycine crystallization achieved by optical trapping
AU - Takahashi, Hozumi
AU - Yoshikawa, Hiroshi Y.
AU - Sugiyama, Teruki
N1 - Publisher Copyright:
© 2024 Elsevier B.V.
PY - 2024/11/1
Y1 - 2024/11/1
N2 - This study investigates concentration dynamics during optical trapping-induced crystallization (OTIC) of glycine using Raman spectroscopy. In-situ Raman spectroscopy demonstrated that tightly focused laser beams induced faster concentration increase and crystal nucleation at higher supersaturation compared to loosely focused beams. Also, by varying numerical aperture (NA) values of the objective lens used, it was revealed that higher NA led to achieving a shorter induction time and higher crystallization probability. Remarkably, optical trapping using objective lenses with higher NA generated stable liquid droplets, inhibiting crystallization until considerably higher supersaturation was realized. These findings elucidate the complex interplay between optical forces, supersaturation, and crystallization dynamics on the mechanism of OTIC and offer a new method for precise control of laser-induced crystallization. We believe that the insights gained by this study pave the way for innovative developments in crystal chemistry and promising advancements in photochemistry.
AB - This study investigates concentration dynamics during optical trapping-induced crystallization (OTIC) of glycine using Raman spectroscopy. In-situ Raman spectroscopy demonstrated that tightly focused laser beams induced faster concentration increase and crystal nucleation at higher supersaturation compared to loosely focused beams. Also, by varying numerical aperture (NA) values of the objective lens used, it was revealed that higher NA led to achieving a shorter induction time and higher crystallization probability. Remarkably, optical trapping using objective lenses with higher NA generated stable liquid droplets, inhibiting crystallization until considerably higher supersaturation was realized. These findings elucidate the complex interplay between optical forces, supersaturation, and crystallization dynamics on the mechanism of OTIC and offer a new method for precise control of laser-induced crystallization. We believe that the insights gained by this study pave the way for innovative developments in crystal chemistry and promising advancements in photochemistry.
KW - Amino acids
KW - Concentration dynamics
KW - Laser-induced crystallization
KW - Optical trapping
KW - Raman spectroscopy
KW - Solution surface
UR - http://www.scopus.com/inward/record.url?scp=85196518459&partnerID=8YFLogxK
U2 - 10.1016/j.jphotochem.2024.115845
DO - 10.1016/j.jphotochem.2024.115845
M3 - Article
AN - SCOPUS:85196518459
SN - 1010-6030
VL - 456
JO - Journal of Photochemistry and Photobiology A: Chemistry
JF - Journal of Photochemistry and Photobiology A: Chemistry
M1 - 115845
ER -