Quartz-based photonic crystal surfaces for multiplexed cancer biomarker detection

Cheng-Sheng Huang, V. Chaudhery, J. Polans, M. Lu, B. T. Cunningham*, A. Pokhriyal, S. George, R. C. Zangar

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

We report for the first time the combination of a quartz-based photonic crystal (PC) with a detection instrument designed to perform label-free (LF) and enhanced fluorescence (EF) imaging for antibody microarray applications. Label-free detection is used to quantify binding density of immobilized capture antibodies. Angle-scanning approach is implemented to achieve more uniform fluorescence enhancement by reducing the coefficient of variation of replicate assays by 20-99% compared to ordinary fluorescence microscopy.

原文English
主出版物標題IEEE SENSORS 2012 - Proceedings
DOIs
出版狀態Published - 2012
事件11th IEEE SENSORS 2012 Conference - Taipei, 台灣
持續時間: 28 10月 201231 10月 2012

出版系列

名字Proceedings of IEEE Sensors

Conference

Conference11th IEEE SENSORS 2012 Conference
國家/地區台灣
城市Taipei
期間28/10/1231/10/12

指紋

深入研究「Quartz-based photonic crystal surfaces for multiplexed cancer biomarker detection」主題。共同形成了獨特的指紋。

引用此