Quantitative evaluation of age-related effects based on oxygenation dynamic signals during the wisconsin card sorting test

Yi Hua Huang; Chung Ming Chen; Yi Min Wang; Chia Wei Sun

doi:10.1109/JSTQE.2020.3019283

Quantitative evaluation of age-related effects based on oxygenation dynamic signals during the wisconsin card sorting test

Yi Hua Huang, Chung Ming Chen, Yi Min Wang, Chia Wei Sun^*

^*此作品的通信作者

光電工程學系

研究成果: Article › 同行評審

摘要

The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks.

原文	English
文章編號	7400106
期刊	IEEE Journal of Selected Topics in Quantum Electronics
卷	27
發行號	4
DOIs	https://doi.org/10.1109/JSTQE.2020.3019283
出版狀態	Published - 1 7月 2020

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10.1109/JSTQE.2020.3019283

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title = "Quantitative evaluation of age-related effects based on oxygenation dynamic signals during the wisconsin card sorting test",

abstract = "The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks. ",

keywords = "Brain age, Functional brain signal, Near-infrared spectroscopy, Wisconsin card sorting test",

author = "Huang, {Yi Hua} and Chen, {Chung Ming} and Wang, {Yi Min} and Sun, {Chia Wei}",

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AU - Huang, Yi Hua

AU - Chen, Chung Ming

AU - Wang, Yi Min

AU - Sun, Chia Wei

PY - 2020/7/1

Y1 - 2020/7/1

N2 - The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks.

AB - The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks.

KW - Brain age

KW - Functional brain signal

KW - Near-infrared spectroscopy

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Quantitative evaluation of age-related effects based on oxygenation dynamic signals during the wisconsin card sorting test

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