Prevalence and subtypes of dementia in a rural Chinese population

Hsiu Chih Liu*, Jong Ling Fuh, Shuu Jiun Wang, Chia Yih Liu, Eric B. Larson, Ker Neng Lin, Hsiao Chien Wang, Zin An Wu, Cheng Huai Lin, Pei Ning Wang


研究成果: Article同行評審

80 引文 斯高帕斯(Scopus)


We conducted a single-stage community-based study of dementia on all registered residents ≥ 65 years in age in a rural Chinese community. Neurologists conducted semistructured interviews and examined all participants; they also interviewed family members in cases where dementia was suspected. The diagnosis was made by consensus according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 3rd ed, revised (DSM-III-R). Among the 2055 contacted individuals, 1736 (84.5%) participated in the study and 44 (13 men and 31 women) were diagnosed as having dementia, including 35 (80%) with probable Alzheimer disease (AD) and 3 (7%) with vascular dementia (VsD). The rates of dementia were 0.5% for ages 65-74 years, 2.9% for ages 75-84 years, and 12.0% for ages 85-101 years. The overall rate was 2.5% for age ≥ 65 years. After controlling for age, neither a lack of formal education nor being a woman was a risk factor for dementia. At 2-year follow-up, 30 of the 44 demented participants had died, yielding a 2-year survival rate of 32%. The present results corroborated our previous findings of lower prevalence rates of dementia among the Chinese than among Western populations, and both genetic and sociocultural factors may have contributed to the low rates. The lack of neuroradiological imaging studies in the present study may have contributed to the finding of an unusually low rate of VsD.

頁(從 - 到)127-134
期刊Alzheimer Disease and Associated Disorders
出版狀態Published - 9月 1998


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