Preparation of targeted anionic lipid-coated polyplexes for MicroRNA delivery

Xiaomeng Huang, Mengzi Zhang, Xinmei Wang, L. James Lee, Robert J. Lee

研究成果: Chapter同行評審

1 引文 斯高帕斯(Scopus)

摘要

As nonviral nucleic acid delivery vehicles, lipid nanoparticles (LNPs) have been widely used. Here we describe the synthesis and evaluation of LNPs based on targeted anionic lipid-coated polyplexs for therapeutic delivery of microRNA (miRNA) mimics. These LNPs are particularly suited for therapeutic delivery of oligonucleotide agents to leukemia cells.

原文English
主出版物標題Methods in Molecular Biology
發行者Humana Press Inc.
頁面201-213
頁數13
DOIs
出版狀態Published - 2016

出版系列

名字Methods in Molecular Biology
1445
ISSN(列印)1064-3745

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