Predicting the volume of tissue activated via electrode impedance during deep brain stimulation

Wei Yi Chuang*, Chang-Po Chao, Kuu-Young Young

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

In a typical deep brain stimulation (DBS) process, doctors depend on the patient's response in tuning the stimulation parameters, which is time consuming. In this process, the volume of tissue activated (VTA) is an important index to describe the stimulated region for helping adjusting suitable stimulation parameters. However, the VTA is hard to measure in clinical trials. The reason is because the brain tissue along the contact of the electrode varies with time since the electrode is implanted chronically. Some previous studies have shown that electrode impedance value significantly affects the size and shape of VTA. However, there is not a precise mathematical model to further investigate the relationship between electrode impedance and VTA. This study thus uses the technique of finite element analysis (FEA) for electromagnetic field simulation, in order to quantify the impact of clinically relevant impedance variability on the VTA during DBS. Through the quantitative description, the VTA can be predicted. Doctors can then tune the stimulation parameters efficiently.

原文English
主出版物標題Proceedings of the 8th IASTED International Conference on Biomedical Engineering, Biomed 2011
頁面77-82
頁數6
DOIs
出版狀態Published - 2011
事件IASTED International Conference on Biomedical Engineering, Biomed 2011 - Innsbruck, Austria
持續時間: 16 2月 201118 2月 2011

出版系列

名字Proceedings of the 8th IASTED International Conference on Biomedical Engineering, Biomed 2011

Conference

ConferenceIASTED International Conference on Biomedical Engineering, Biomed 2011
國家/地區Austria
城市Innsbruck
期間16/02/1118/02/11

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