Precise cell trapping with structure-confined dielectrophoresis

S. M. Yang*, T. H. Punde, H. P. Chen, C. W. Lin, S. Shilpa, V. P. Srinivasu, Y. T. Lu, Long Hsu, C. H. Liu

*此作品的通信作者

研究成果: Conference contribution同行評審

1 引文 斯高帕斯(Scopus)

摘要

We present a precise cell trapping platform, structure-confined electrophoresis, which utilize microchannel with lateral cavity to bend the electric field for generating positive dielectrophoresis (DEP) force. A revealed metal electrode, 10μm × 20μm, is placed inside the deep place of cavity. Providing stronger DEP force to trap mobile cells and reducing the flow shear stress acting on the trapped cell are two advantages of the cavity design. The cells trapping efficiency are increased by the multi-channel design. Five microchannels provide 400 cells trapping locations. Finally, we calibrate the relationship between flow velocity, applied ac voltage and the trapped cells number. This application utilizing structure to confine the electric field distribution is not only to provide the accurate cells trapping function, but to be a platform for electrical fusion approach of trapped cells.

原文English
主出版物標題2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
頁面394-397
頁數4
DOIs
出版狀態Published - 1 9月 2011
事件2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China
持續時間: 5 6月 20119 6月 2011

出版系列

名字2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Conference

Conference2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
國家/地區China
城市Beijing
期間5/06/119/06/11

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