Optimization for power is always one of the most important design objectives in modern nanometer IC design. Recent studies have shown the effectiveness of applying multi-bit flip-flops to save the power consumption of the clock network. However, all the previous works applied multi-bit flip-flops at earlier design stages, which could be very difficult to carry out the trade-off among power, timing, and other design objectives. This paper presents a novel power optimization method by incrementally applying more multi-bit flip-flops at the post-placement stage to gain more clock power saving while considering the placement density and timing slack constraints, and simultaneously minimizing interconnecting wirelength. Experimental results based on the industry benchmark circuits show that our approach is very effective and efficient, which can be seamlessly integrated in modern design flow.