PMMA-based capillary electrophoresis electrochemical detection microchip fabrication

Ray-Hua Horng; Pin Han; Hung Yu Chen; Kuan Wen Lin; Tung Mung Tsai; Jyh Myng Zen

doi:10.1088/0960-1317/15/1/002

PMMA-based capillary electrophoresis electrochemical detection microchip fabrication

Ray-Hua Horng^*, Pin Han, Hung Yu Chen, Kuan Wen Lin, Tung Mung Tsai, Jyh Myng Zen

^*此作品的通信作者

電子研究所

研究成果: Article › 同行評審

31 引文斯高帕斯（Scopus）

摘要

In this paper, a 50 μm (depth) × 50 μm (width) microfluidic channel is made on a poly(methyl methacrylate) (PMMA) substrate using thick photoresist. Openings were drilled for buffer reservoirs on an additional piece of PMMA. A final PMMA/patterned photoresist/PMMA sandwich configuration was completed using a bonding process. The thick photoresist was used as the adhesion layer and also as the microfluidic system. Using screen-printed technology for carbon and silver electrode fabrication, the microchip electrophoretic device functions were demonstrated. Successful detection of uric acid and L-ascorbic acid (the main components in human urine) validates the functionality of the proposed system. Successful ascorbic and uric acid separation in a sample from a urine donor who had consumed 500 mg of vitamins verified the proposed biochip.

原文	English
頁（從 - 到）	6-10
頁數	5
期刊	Journal of Micromechanics and Microengineering
卷	15
發行號	1
DOIs	https://doi.org/10.1088/0960-1317/15/1/002
出版狀態	Published - 1月 2005

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10.1088/0960-1317/15/1/002

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引用此

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AU - Han, Pin

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AU - Zen, Jyh Myng

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PMMA-based capillary electrophoresis electrochemical detection microchip fabrication

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