Plasmonic nanoparticles in agarose gel and filter paper-integrated microfluidic devices for SERS detection of molecules

Li An Wu, Yun Chu Chen, Wen Chi Pai, Yun Hsian Hsu, Yih Fan Chen

研究成果: Conference contribution同行評審

1 引文 斯高帕斯(Scopus)

摘要

We will present surface enhanced Raman spectroscopy (SERS) detection of molecules using plasmonic nanoparticles that are embedded in agarose gel and in filter paper-integrated microfluidic channels, respectively. It has been known that, when SERS detection is performed in complex fluids such as cell culture media, a method to reduce interferences from a variety of molecules in the fluids on the detection results is very important. If continuous monitoring of molecules in cell culture media is needed, there should be a method to prevent large molecules such as proteins from reaching SERS substrates when sample solutions flow over the substrates. Since both agarose gel and filter paper can be used to separate molecules by size, in this study we have integrated them with plasmonic nanoparticles for SERS detection in complex fluids. We will report how to use filter paper-integrated microfluidic channels to detect melamine and sodium thiocyanate (NaSCN) in milk using SERS. In addition, we will demonstrate how to use plasmonic agarose gels to detect illegal drug in urine.

原文English
主出版物標題Plasmonics in Biology and Medicine XVII
編輯Tuan Vo-Dinh, Ho-Pui A. Ho, Krishanu Ray
發行者SPIE
ISBN(電子)9781510632776
DOIs
出版狀態Published - 2020
事件Plasmonics in Biology and Medicine XVII 2020 - San Francisco, United States
持續時間: 2 2月 20203 2月 2020

出版系列

名字Progress in Biomedical Optics and Imaging - Proceedings of SPIE
11257
ISSN(列印)1605-7422

Conference

ConferencePlasmonics in Biology and Medicine XVII 2020
國家/地區United States
城市San Francisco
期間2/02/203/02/20

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