Peak-finding algorithms

Jui-Hung Hung, Zhiping Weng

研究成果: Article同行評審

摘要

Microarray and next-generation sequencing technologies have greatly expedited the discovery of genomic DNA that can be enriched using various biochemical methods. Chromatin immunoprecipitation (ChIP) is a general method for enriching chromatin fragments that are specifically recognized by an antibody. The resulting DNA fragments can be assayed by microarray (ChIP-chip) or sequencing (ChIP-seq). This introduction focuses on ChIP-seq data analysis. The first step of analyzing ChIP-seq data is identifying regions in the genome that are enriched in a ChIP sample; these regions are called peaks.

原文English
頁(從 - 到)197-203
頁數7
期刊Cold Spring Harbor Protocols
2017
發行號3
DOIs
出版狀態Published - 1 三月 2017

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