Pandemic aspect of dexamethasone: Molecular mechanisms and clinical application

Anna F.Y. Li, Chia Lin Wang, Hsiao Yun Tai, Yun Ju Fu, Fu Ting Tsai, Yi Ching Tsai, Yu Ling Ko, Mei Jane Li, Chiou Chyn Lin, Tai Jay Chang*

*此作品的通信作者

研究成果: Article同行評審

7 引文 斯高帕斯(Scopus)

摘要

The rapid spread of coronavirus disease (COVID-19) in many countries has caused inconvenience in conducting daily life activities, and even deaths. Dexamethasone is a corticosteroid applied in clinical medicine since 1957, especially in immune therapy fields. Herein, we present the characteristics of Dexamethasone, from molecular mechanisms such as genomic and nongenomic pathways by cellular signal regulations, to clinical applications in various phases of the disease. During COVID-19 pandemic, Dexamethasone given to patients who required oxygen or ventilation therapy showed improved life efficacy.

原文English
頁(從 - 到)245-247
頁數3
期刊Journal of the Chinese Medical Association
84
發行號3
DOIs
出版狀態Published - 3月 2021

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