Palladium(II)-catalyzed mono-and bis-alkenylation of N-acetyl-2-aminobiaryls through regioselective C-H bond activation

Pratheepkumar Annamalai, Kou Chi Hsu, Selvam Raju, Huan Chang Hsiao, Chih Wei Chou, Gu Ying Lin, Cheng Ming Hsieh, Pei Ling Chen, Yi Hung Liu, Shih-Ching Chuang*

*此作品的通信作者

研究成果: Article同行評審

19 引文 斯高帕斯(Scopus)

摘要

We developed palladium-catalyzed oxidative coupling of olefins with N-acyl 2-aminobiaryls through a sequence of ortho C-H bond activation/alkene insertion/reductive elimination. Furthermore, we controlled the selectivity of mono-and bis-alkenylation products with the solvent effect. The developed protocol was promising for a broad substrate scope ranging from activated olefins with a wide variety of functional groups to unactivated olefins.

原文English
頁(從 - 到)3840-3856
頁數17
期刊Journal of Organic Chemistry
83
發行號7
DOIs
出版狀態Published - 6 4月 2018

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