Palladium-Catalyzed Selective Aryl Ring C–H Activation of N-Acyl-2-aminobiaryls: Efficient Access to Multiaryl-Substituted Naphthalenes

Pratheepkumar Annamalai, Wu Yin Chen, Selvam Raju, Kou Chi Hsu, Nitinkumar Satyadev Upadhyay, Chien Hong Cheng*, Shih-Ching Chuang

*此作品的通信作者

研究成果: Article同行評審

16 引文 斯高帕斯(Scopus)

摘要

Palladium-catalyzed cycloaromatization of N-acyl-2-aminobiaryls, through a sequence of ortho C−H bond activation/alkyne insertion/meta C−H bond activation/alkyne insertion, was developed. An efficient synthesis of multiaryl-substituted naphthalenes, N-[2-(5,6,7,8-tetraarylnaphthalen-1-yl)aryl]acetamides, was demonstrated using molecular oxygen as the sole oxidant. Furthermore, through Buchwald's synthetic protocol, two compounds were converted into corresponding fluorescent carbazoles in 30–40% yield by intramolecular C−N bond formation. (Figure presented.).

原文English
頁(從 - 到)3642-3648
頁數7
期刊Advanced Synthesis and Catalysis
358
發行號22
DOIs
出版狀態Published - 1 一月 2016

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