Optimising FRET-efficiency of Nd3+-sensitised upconversion nanocomposites by shortening the emitter-photosensitizer distance

Syue Liang Lin, Cheng Allen Chang

研究成果: Article同行評審

13 引文 斯高帕斯(Scopus)

摘要

Nd3+-Sensitised luminescent upconversion nanoparticles (UCNPs) have gained interest recently as theranostics due to their near-infrared (NIR) light excitation with a better tissue penetration depth. One example is the core/shell design NaYF4:Yb,Er@Nd,Yb. When harvesting the upconversion energy in such architectures, the long emitter-photosensitizer (i.e. Er3+-PS) distances lead to inefficient Förster resonance energy transfer (FRET). Herein, we report a new nanocomposite NaYF4:Nd,Yb@Yb@Yb,Er@Y with Nd3+ ions in the core and Er3+ ions in the shell to shorten the Er-PS distance to achieve better FRET. Furthermore, an outer non-emitting protective Y3+ shell and a conducting Yb3+ shell reduced surface quenching and Er3+-to-Nd3+ energy back transfer effects, respectively. The upconversion FRET and downshifting emission efficiencies were simultaneously optimised by adjusting the thickness of the Y3+ shell, and the FRET efficiency was at least 3.7 times that of the reference NaYF4:Yb,Er@Yb@Nd,Yb@Y in a photodynamic therapy (PDT) model.

原文English
頁(從 - 到)8742-8749
頁數8
期刊Nanoscale
12
發行號16
DOIs
出版狀態Published - 28 4月 2020

指紋

深入研究「Optimising FRET-efficiency of Nd3+-sensitised upconversion nanocomposites by shortening the emitter-photosensitizer distance」主題。共同形成了獨特的指紋。

引用此