摘要
A series of novel resorcin[4]arenes with extended π systems have been synthesised and developed as potassium-selective transporters. Resorcin[4]arenes that feature crown ether moieties function as efficient carriers of K+ across bulk liquid membranes showing enhanced selectivity over the other alkali metal ions relative to a model system (benzo[15]crown-5). Incorporation of functionalities suitable for pore formation, in addition to an extra annulus of aromatic residues, gives molecules which have remarkable ion-channel-mimicking behaviour in a biological lipid bilayer with outstanding K+/Na+ selectivity.
原文 | English |
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頁(從 - 到) | 3474-3481 |
頁數 | 8 |
期刊 | Chemistry - A European Journal |
卷 | 7 |
發行號 | 16 |
DOIs | |
出版狀態 | Published - 17 8月 2001 |