Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

Nidhi Gupta; Yang Hsiang Chan; Sampa Saha; Ming Ho Liu

doi:10.1002/asia.202001348

Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

Nidhi Gupta, Yang Hsiang Chan^*, Sampa Saha, Ming Ho Liu

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研究成果: Review article › 同行評審

16 引文斯高帕斯（Scopus）

摘要

Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.

原文	English
頁（從 - 到）	175-184
頁數	10
期刊	Chemistry - An Asian Journal
卷	16
發行號	3
DOIs	https://doi.org/10.1002/asia.202001348
出版狀態	Published - 1 2月 2021

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title = "Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging",

abstract = "Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.",

keywords = "deep-tissue, fluorescence, NIR-II, optical properties, polymer dots",

author = "Nidhi Gupta and Chan, {Yang Hsiang} and Sampa Saha and Liu, {Ming Ho}",

note = "Publisher Copyright: {\textcopyright} 2020 Wiley-VCH GmbH",

year = "2021",

month = feb,

day = "1",

doi = "10.1002/asia.202001348",

language = "English",

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T1 - Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

AU - Gupta, Nidhi

AU - Chan, Yang Hsiang

AU - Saha, Sampa

AU - Liu, Ming Ho

PY - 2021/2/1

Y1 - 2021/2/1

N2 - Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.

AB - Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.

KW - deep-tissue

KW - fluorescence

KW - NIR-II

KW - optical properties

KW - polymer dots

UR - http://www.scopus.com/inward/record.url?scp=85098156742&partnerID=8YFLogxK

U2 - 10.1002/asia.202001348

DO - 10.1002/asia.202001348

M3 - Review article

C2 - 33331122

AN - SCOPUS:85098156742

SN - 1861-4728

VL - 16

SP - 175

EP - 184

JO - Chemistry - An Asian Journal

JF - Chemistry - An Asian Journal

IS - 3

ER -

Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

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