Natural products from the culture broth of an actinobacteria Streptomyces sp. M5205 and evaluation of their antifungal activity

Jih Jung Chen, Ming Jen Cheng*, Min Tseng, Ming Der Wu, Jing Ru Weng

*此作品的通信作者

研究成果: Article同行評審

摘要

One previously undescribed trinorditerpene analog, M5205 (1), together with four known triterpenes, betulinic acid (2), betulin (3), messagenic acid D (4), and betulonic acid (5), were isolated from the EtOAc extract of the culture broth of the actinomycete Streptomyces sp. M5205. One previously undescribed sesquiterpene analog, M5205 (1), together with four known analogs, betulinic acid (2), betulin (3), messagenic acid D (4), and betulonic acid (5), were isolated from the EtOAc extract of the culture broth of the actinomycete Streptomyces sp. M5205. The structures of all isolates were elucidated on the basis of extensive analyses of spectroscopic data and comparison with literature data. Their antifungal activity was also evaluated. Our results showed that 4 constituents (Compounds 1 & 335) possessed mild antifungal activity against Fusarium sp. LC8, Neopestalotiopsis sp. BCRC 35002, and Colletotrichum gloeosporioides BCRC 35178. It is worth mentioning that the chemical composition of the type strain Streptomyces sp. M5205 has never been studied.

原文English
頁(從 - 到)59-63
頁數5
期刊Phytochemistry Letters
59
DOIs
出版狀態Published - 2月 2024

指紋

深入研究「Natural products from the culture broth of an actinobacteria Streptomyces sp. M5205 and evaluation of their antifungal activity」主題。共同形成了獨特的指紋。

引用此