摘要
We present a sensitive nano-optical fiber biosensor made by shaping a fiber to form a taper with a tip size under 100 nm.A 40-nm-thick layer of gold is coated around the tapered fiber and a surface plasmon wave is excited near the tip to achieve a sensitivity of the reflective index unit of ∼4000 (% RIU-1) in the intensity measurement. A 3-D coded finite-difference time-domain approach verifies the excitation of the surface plasmon wave and the differences among its intensities in media of various refractive indices. The nanotip fiber sensor has the merits of a low background light and an ultrasmall detection region. Only a microliter of sample solution is required for detection.
原文 | English |
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文章編號 | 014032 |
期刊 | Journal of Biomedical Optics |
卷 | 11 |
發行號 | 1 |
DOIs | |
出版狀態 | Published - 1月 2006 |