Multi-layer planar micro-coils chip as actuators and heaters for biological applications

Chen Chia Chen; Shih Hsun Hsu; Chen Hsiang Sang; Chih Chyau Yang; Chien Ming Wu; Chun Ming Huang; Jeng-Tzong Sheu

doi:10.1109/BioCAS.2012.6418414

Multi-layer planar micro-coils chip as actuators and heaters for biological applications

Chen Chia Chen^*, Shih Hsun Hsu, Chen Hsiang Sang, Chih Chyau Yang, Chien Ming Wu, Chun Ming Huang, Jeng-Tzong Sheu

^*此作品的通信作者

奈米科技碩博班

研究成果: Conference contribution › 同行評審

摘要

In this paper, a multi-functional of multi-layer planar micro-coils chip is demonstrated to play as actuators and heaters. For playing as actuators, the micro-coil generate local magnetic field with applied current of 15 mA to quickly manipulated magnetic beads to center of micro-coil within one minute. For functioning as heaters, the micro-coil heater can be quickly heated up to denatured temperature of 95 °C with input power of 50.5 mW, and its heating and cooling rate are 19.7 and 11.8 °C/s, respectively. For the typical 25 polymerase chain reaction (PCR) cycles, it took only 770 seconds. To further shrink and optimize the multi-layer planar micro-coils chip can be possibly used to manipulate single cell with magnetic beads to specific region and analyze its gene sequence by using single cell PCR technique.

原文	English
主出版物標題	2012 IEEE Biomedical Circuits and Systems Conference
主出版物子標題	Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications
頁面	392-395
頁數	4
DOIs	https://doi.org/10.1109/BioCAS.2012.6418414
出版狀態	Published - 1 12月 2012
事件	2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Hsinchu, Taiwan 持續時間: 28 11月 2012 → 30 11月 2012

出版系列

名字	2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications

Conference

Conference	2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012
國家/地區	Taiwan
城市	Hsinchu
期間	28/11/12 → 30/11/12

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10.1109/BioCAS.2012.6418414

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Link to publication in Scopus

引用此

Chen, C. C., Hsu, S. H., Sang, C. H., Yang, C. C., Wu, C. M., Huang, C. M., & Sheu, J-T. (2012). Multi-layer planar micro-coils chip as actuators and heaters for biological applications. 於 2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications (頁 392-395). 文章 6418414 (2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications). https://doi.org/10.1109/BioCAS.2012.6418414

Chen, Chen Chia ; Hsu, Shih Hsun ; Sang, Chen Hsiang 等. / Multi-layer planar micro-coils chip as actuators and heaters for biological applications. 2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications. 2012. 頁 392-395 (2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications).

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title = "Multi-layer planar micro-coils chip as actuators and heaters for biological applications",

abstract = "In this paper, a multi-functional of multi-layer planar micro-coils chip is demonstrated to play as actuators and heaters. For playing as actuators, the micro-coil generate local magnetic field with applied current of 15 mA to quickly manipulated magnetic beads to center of micro-coil within one minute. For functioning as heaters, the micro-coil heater can be quickly heated up to denatured temperature of 95 °C with input power of 50.5 mW, and its heating and cooling rate are 19.7 and 11.8 °C/s, respectively. For the typical 25 polymerase chain reaction (PCR) cycles, it took only 770 seconds. To further shrink and optimize the multi-layer planar micro-coils chip can be possibly used to manipulate single cell with magnetic beads to specific region and analyze its gene sequence by using single cell PCR technique.",

author = "Chen, {Chen Chia} and Hsu, {Shih Hsun} and Sang, {Chen Hsiang} and Yang, {Chih Chyau} and Wu, {Chien Ming} and Huang, {Chun Ming} and Jeng-Tzong Sheu",

year = "2012",

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day = "1",

doi = "10.1109/BioCAS.2012.6418414",

language = "English",

isbn = "9781467322935",

series = "2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications",

pages = "392--395",

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note = "2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 ; Conference date: 28-11-2012 Through 30-11-2012",

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Chen, CC, Hsu, SH, Sang, CH, Yang, CC, Wu, CM, Huang, CM & Sheu, J-T 2012, Multi-layer planar micro-coils chip as actuators and heaters for biological applications. 於 2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications., 6418414, 2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications, 頁 392-395, 2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012, Hsinchu, Taiwan, 28/11/12. https://doi.org/10.1109/BioCAS.2012.6418414

Multi-layer planar micro-coils chip as actuators and heaters for biological applications. / Chen, Chen Chia; Hsu, Shih Hsun; Sang, Chen Hsiang 等.
2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications. 2012. p. 392-395 6418414 (2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications).

研究成果: Conference contribution › 同行評審

TY - GEN

T1 - Multi-layer planar micro-coils chip as actuators and heaters for biological applications

AU - Chen, Chen Chia

AU - Hsu, Shih Hsun

AU - Sang, Chen Hsiang

AU - Yang, Chih Chyau

AU - Wu, Chien Ming

AU - Huang, Chun Ming

AU - Sheu, Jeng-Tzong

PY - 2012/12/1

Y1 - 2012/12/1

N2 - In this paper, a multi-functional of multi-layer planar micro-coils chip is demonstrated to play as actuators and heaters. For playing as actuators, the micro-coil generate local magnetic field with applied current of 15 mA to quickly manipulated magnetic beads to center of micro-coil within one minute. For functioning as heaters, the micro-coil heater can be quickly heated up to denatured temperature of 95 °C with input power of 50.5 mW, and its heating and cooling rate are 19.7 and 11.8 °C/s, respectively. For the typical 25 polymerase chain reaction (PCR) cycles, it took only 770 seconds. To further shrink and optimize the multi-layer planar micro-coils chip can be possibly used to manipulate single cell with magnetic beads to specific region and analyze its gene sequence by using single cell PCR technique.

AB - In this paper, a multi-functional of multi-layer planar micro-coils chip is demonstrated to play as actuators and heaters. For playing as actuators, the micro-coil generate local magnetic field with applied current of 15 mA to quickly manipulated magnetic beads to center of micro-coil within one minute. For functioning as heaters, the micro-coil heater can be quickly heated up to denatured temperature of 95 °C with input power of 50.5 mW, and its heating and cooling rate are 19.7 and 11.8 °C/s, respectively. For the typical 25 polymerase chain reaction (PCR) cycles, it took only 770 seconds. To further shrink and optimize the multi-layer planar micro-coils chip can be possibly used to manipulate single cell with magnetic beads to specific region and analyze its gene sequence by using single cell PCR technique.

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M3 - Conference contribution

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SN - 9781467322935

T3 - 2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications

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BT - 2012 IEEE Biomedical Circuits and Systems Conference

T2 - 2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012

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Chen CC, Hsu SH, Sang CH, Yang CC, Wu CM, Huang CM 等. Multi-layer planar micro-coils chip as actuators and heaters for biological applications. 於 2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications. 2012. p. 392-395. 6418414. (2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications). doi: 10.1109/BioCAS.2012.6418414

Multi-layer planar micro-coils chip as actuators and heaters for biological applications

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