Monopolar Biphasic Stimulator with Discharge Function and Negative Level Shifter for Neuromodulation SoC Integration in Low-Voltage CMOS Process

Chia Chi Hsieh, Ming-Dou Ker*

*此作品的通信作者

研究成果: Article同行評審

28 引文 斯高帕斯(Scopus)

摘要

A 16-channel monopolar biphasic stimulator chip with discharge function for biomedical applications is proposed and designed. To provide monopolar biphasic stimulus currents, the positive (6V) and the negative (-6V) voltage sources are supported to generate the desired current pulses of ±3 mA. The monopolar biphasic stimulator chip was fabricated in a 0.18-μm 1.8-V/3.3-V CMOS process with the common grounded p-Type substrate. The overstress and reliability issues on the low-voltage transistors in the stimulator circuits were fully overcome by circuit design. The silicon area of each single channel only occupies 0.08 mm2 and the output level of stimulus current is up to ±3 mA. By applying the discharge function, safety concern of unbalanced charge in neuro-stimulation can be dealt properly. The residual average dc current is less than 3.42 nA after discharge is activated. Moreover, this chip has also been verified with both in-vitro imitation measurement and in-vivo animal test.

原文English
文章編號9447922
頁(從 - 到)568-579
頁數12
期刊IEEE Transactions on Biomedical Circuits and Systems
15
發行號3
DOIs
出版狀態Published - 6月 2021

指紋

深入研究「Monopolar Biphasic Stimulator with Discharge Function and Negative Level Shifter for Neuromodulation SoC Integration in Low-Voltage CMOS Process」主題。共同形成了獨特的指紋。

引用此