Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals

Yi Hui Wu; Yi Huan Ou-Yang; Chiung-Chu Chen; Chen Yi Lee; Chung-Yu Wu; Ming-Dou Ker

doi:10.1109/EMBC44109.2020.9175384

Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals

Yi Hui Wu^*, Yi Huan Ou-Yang, Chiung-Chu Chen, Chen Yi Lee, Chung-Yu Wu, Ming-Dou Ker

^*此作品的通信作者

研究成果: Conference contribution › 同行評審

1 引文斯高帕斯（Scopus）

摘要

A miniaturized intracerebral potential recorder for long-term local field potential (LFP) of deep brain signals is proposed. LFP can be recorded by deep brain electrodes. The abnormal beta-band oscillation of LFP in subthalamic nucleus and internal globus pallidus in patients with Parkinson's disease (PD) are associated with the severity of the symptoms. The LFP signal from patients who have been implanted with deep brain electrode can be monitored by our system for at least 24 hours in real time. Graphical user interface has also been developed for use by medical personnel. Imitation experiments and in vivo experiments were performed to successfully verify that our system can measure LFP signals. With 24-hour intracerebral signals, researchers can analyze what is happened in the brain in daily life. In the future, more effective PD treatment can be developed, such as intelligent closed-loop deep brain stimulation.

原文	English
主出版物標題	42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society
主出版物子標題	Enabling Innovative Technologies for Global Healthcare, EMBC 2020
發行者	Institute of Electrical and Electronics Engineers Inc.
頁面	5188-5191
頁數	4
ISBN（電子）	9781728119908
ISBN（列印）	978-1-7281-1991-5
DOIs	https://doi.org/10.1109/EMBC44109.2020.9175384
出版狀態	Published - 20 7月 2020
事件	42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020 - Montreal, Canada 持續時間: 20 7月 2020 → 24 7月 2020

出版系列

名字	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
卷	2020-July
ISSN（列印）	1557-170X

Conference

Conference	42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020
國家/地區	Canada
城市	Montreal
期間	20/07/20 → 24/07/20

存取文件

10.1109/EMBC44109.2020.9175384

其它文件與鏈接

Link to publication in Scopus

引用此

Wu, Y. H., Ou-Yang, Y. H., Chen, C-C., Lee, C. Y., Wu, C-Y., & Ker, M-D. (2020). Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals. 於 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020 (頁 5188-5191). [9175384] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; 卷 2020-July). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC44109.2020.9175384

Wu, Yi Hui ; Ou-Yang, Yi Huan ; Chen, Chiung-Chu 等. / Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals. 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020. Institute of Electrical and Electronics Engineers Inc., 2020. 頁 5188-5191 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

@inproceedings{dfb0790447544109aa78ab82176b484d,

title = "Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals",

abstract = "A miniaturized intracerebral potential recorder for long-term local field potential (LFP) of deep brain signals is proposed. LFP can be recorded by deep brain electrodes. The abnormal beta-band oscillation of LFP in subthalamic nucleus and internal globus pallidus in patients with Parkinson's disease (PD) are associated with the severity of the symptoms. The LFP signal from patients who have been implanted with deep brain electrode can be monitored by our system for at least 24 hours in real time. Graphical user interface has also been developed for use by medical personnel. Imitation experiments and in vivo experiments were performed to successfully verify that our system can measure LFP signals. With 24-hour intracerebral signals, researchers can analyze what is happened in the brain in daily life. In the future, more effective PD treatment can be developed, such as intelligent closed-loop deep brain stimulation.",

keywords = "beta-band oscillation, deep brain signals, graphical user interface, local field potential, Parkinson's disease",

author = "Wu, {Yi Hui} and Ou-Yang, {Yi Huan} and Chiung-Chu Chen and Lee, {Chen Yi} and Chung-Yu Wu and Ming-Dou Ker",

note = "Publisher Copyright: {\textcopyright} 2020 IEEE. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.; 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020 ; Conference date: 20-07-2020 Through 24-07-2020",

year = "2020",

month = jul,

day = "20",

doi = "10.1109/EMBC44109.2020.9175384",

language = "English",

isbn = "978-1-7281-1991-5",

series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

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Wu, YH, Ou-Yang, YH, Chen, C-C, Lee, CY, Wu, C-Y & Ker, M-D 2020, Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals. 於 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020., 9175384, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 卷 2020-July, Institute of Electrical and Electronics Engineers Inc., 頁 5188-5191, 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020, Montreal, Canada, 20/07/20. https://doi.org/10.1109/EMBC44109.2020.9175384

Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals. / Wu, Yi Hui; Ou-Yang, Yi Huan; Chen, Chiung-Chu 等.
42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020. Institute of Electrical and Electronics Engineers Inc., 2020. p. 5188-5191 9175384 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; 卷 2020-July).

研究成果: Conference contribution › 同行評審

TY - GEN

T1 - Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals

AU - Wu, Yi Hui

AU - Ou-Yang, Yi Huan

AU - Chen, Chiung-Chu

AU - Lee, Chen Yi

AU - Wu, Chung-Yu

AU - Ker, Ming-Dou

PY - 2020/7/20

Y1 - 2020/7/20

N2 - A miniaturized intracerebral potential recorder for long-term local field potential (LFP) of deep brain signals is proposed. LFP can be recorded by deep brain electrodes. The abnormal beta-band oscillation of LFP in subthalamic nucleus and internal globus pallidus in patients with Parkinson's disease (PD) are associated with the severity of the symptoms. The LFP signal from patients who have been implanted with deep brain electrode can be monitored by our system for at least 24 hours in real time. Graphical user interface has also been developed for use by medical personnel. Imitation experiments and in vivo experiments were performed to successfully verify that our system can measure LFP signals. With 24-hour intracerebral signals, researchers can analyze what is happened in the brain in daily life. In the future, more effective PD treatment can be developed, such as intelligent closed-loop deep brain stimulation.

AB - A miniaturized intracerebral potential recorder for long-term local field potential (LFP) of deep brain signals is proposed. LFP can be recorded by deep brain electrodes. The abnormal beta-band oscillation of LFP in subthalamic nucleus and internal globus pallidus in patients with Parkinson's disease (PD) are associated with the severity of the symptoms. The LFP signal from patients who have been implanted with deep brain electrode can be monitored by our system for at least 24 hours in real time. Graphical user interface has also been developed for use by medical personnel. Imitation experiments and in vivo experiments were performed to successfully verify that our system can measure LFP signals. With 24-hour intracerebral signals, researchers can analyze what is happened in the brain in daily life. In the future, more effective PD treatment can be developed, such as intelligent closed-loop deep brain stimulation.

KW - beta-band oscillation

KW - deep brain signals

KW - graphical user interface

KW - local field potential

KW - Parkinson's disease

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U2 - 10.1109/EMBC44109.2020.9175384

DO - 10.1109/EMBC44109.2020.9175384

M3 - Conference contribution

AN - SCOPUS:85091013610

SN - 978-1-7281-1991-5

T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

SP - 5188

EP - 5191

BT - 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020

Y2 - 20 July 2020 through 24 July 2020

ER -

Wu YH, Ou-Yang YH, Chen C-C, Lee CY, Wu C-Y, Ker M-D. Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals. 於 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020. Institute of Electrical and Electronics Engineers Inc. 2020. p. 5188-5191. 9175384. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC44109.2020.9175384

Miniaturized Intracerebral Potential Recorder for Long-Term Local Field Potential of Deep Brain Signals

摘要

出版系列

Conference

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指紋

引用此