Microsurface plasmon resonance biosensing based on gold-nanoparticle film

Xin Hong*, Fu Jen Kao

*此作品的通信作者

研究成果: Article同行評審

20 引文 斯高帕斯(Scopus)

摘要

We use a gold-nanoparticle coated film to achieve highly spatially resolved biosensing that is based on localized surface-plasmon resonance. Unlike the planar gold film employed for conventional surface-plasmon resonance sensing, the gold-nanoparticle film relies exclusively on shifting of the peak extinction wavelength for detection of biointeraetion and does not depend critically on the angle of incidence. These characteristics permit integration of surface-plasmon resonance with large-numerical-aperture optics to achieve biosensing with high sensitivity and spatial resolution as high as 25 μm.

原文English
頁(從 - 到)2868-2873
頁數6
期刊Applied Optics
43
發行號14
DOIs
出版狀態Published - 10 5月 2004

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